TY  - GEN
AU  - Raucy,Judy
AU  - Warfe,Lyndon
AU  - Yueh,Mei-Fei
AU  - Allen,Scott W
TI  - A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system
SN  - 0022-3565
PY  - 2002///1021
KW  - Base Sequence
KW  - Blotting, Northern
KW  - Cell Line, Transformed
KW  - Cell Survival
KW  - physiology
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - biosynthesis
KW  - DNA Primers
KW  - Enzyme Induction
KW  - Genes, Reporter
KW  - Hepatocytes
KW  - metabolism
KW  - Humans
KW  - Liver
KW  - Lovastatin
KW  - analogs & derivatives
KW  - Luciferases
KW  - genetics
KW  - Mifepristone
KW  - pharmacology
KW  - Mixed Function Oxygenases
KW  - Omeprazole
KW  - Polychlorinated Dibenzodioxins
KW  - Pregnane X Receptor
KW  - RNA, Messenger
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Receptors, Steroid
KW  - Recombinant Fusion Proteins
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Rifampin
KW  - Transcription, Genetic
KW  - drug effects
KW  - Transfection
KW  - methods
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1124/jpet.102.038653
ER  -