TY - GEN AU - Lammich,Sven AU - Okochi,Masayasu AU - Takeda,Masatoshi AU - Kaether,Christoph AU - Capell,Anja AU - Zimmer,Ann-Katrin AU - Edbauer,Dieter AU - Walter,Jochen AU - Steiner,Harald AU - Haass,Christian TI - Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide SN - 0021-9258 PY - 2003///0107 KW - Alzheimer Disease KW - metabolism KW - Amino Acid Sequence KW - Amyloid Precursor Protein Secretases KW - Amyloid beta-Peptides KW - Amyloid beta-Protein Precursor KW - genetics KW - Animals KW - Aspartic Acid Endopeptidases KW - Carbamates KW - pharmacology KW - Cell Line KW - Cell Membrane KW - Dipeptides KW - Endopeptidases KW - Enzyme Inhibitors KW - Fibroblasts KW - cytology KW - Humans KW - Hyaluronan Receptors KW - Membrane Proteins KW - Mice KW - Mice, Knockout KW - Molecular Sequence Data KW - Peptides KW - Presenilin-1 KW - Presenilin-2 KW - Protein Structure, Tertiary KW - Sequence Alignment KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Triglycerides KW - gamma-Aminobutyric Acid KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M206872200 ER -