TY  - GEN
AU  - Chen,Jun
AU  - Seebohm,Guiscard
AU  - Sanguinetti,Michael C
TI  - Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels
SN  - 0027-8424
PY  - 2002///1028
KW  - Amino Acid Sequence
KW  - Amino Acids, Aromatic
KW  - chemistry
KW  - Animals
KW  - Binding Sites
KW  - genetics
KW  - Cation Transport Proteins
KW  - Cisapride
KW  - pharmacology
KW  - DNA-Binding Proteins
KW  - Drosophila Proteins
KW  - antagonists & inhibitors
KW  - ERG1 Potassium Channel
KW  - Ether-A-Go-Go Potassium Channels
KW  - Female
KW  - Humans
KW  - In Vitro Techniques
KW  - Long QT Syndrome
KW  - chemically induced
KW  - Membrane Potentials
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Oocytes
KW  - metabolism
KW  - Potassium Channel Blockers
KW  - Potassium Channels
KW  - Potassium Channels, Voltage-Gated
KW  - Protein Structure, Tertiary
KW  - Recombinant Proteins
KW  - Sequence Homology, Amino Acid
KW  - Trans-Activators
KW  - Transcriptional Regulator ERG
KW  - Xenopus laevis
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1073/pnas.192367299
ER  -