TY  - GEN
AU  - Ulloa,Luis
AU  - Ochani,Mahendar
AU  - Yang,Huan
AU  - Tanovic,Mahira
AU  - Halperin,Daniel
AU  - Yang,Runkuan
AU  - Czura,Christopher J
AU  - Fink,Mitchell P
AU  - Tracey,Kevin J
TI  - Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
SN  - 0027-8424
PY  - 2002///1028
KW  - Animals
KW  - Cell Line
KW  - Endotoxemia
KW  - complications
KW  - Enzyme Activation
KW  - drug effects
KW  - HMGB1 Protein
KW  - metabolism
KW  - Lipopolysaccharides
KW  - toxicity
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mitogen-Activated Protein Kinases
KW  - NF-kappa B
KW  - genetics
KW  - Pyruvates
KW  - administration & dosage
KW  - RNA, Messenger
KW  - Sepsis
KW  - Signal Transduction
KW  - Systemic Inflammatory Response Syndrome
KW  - drug therapy
KW  - Tumor Necrosis Factor-alpha
KW  - p38 Mitogen-Activated Protein Kinases
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1073/pnas.192222999
ER  -