Freytag, Svend O <br/><br/>
Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer.  [electronic resource] 

 -  Cancer research  Sep 2002 
 - 4968-76 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenoviruses, Human--genetics<br/>Aged<br/>Aged, 80 and over<br/>Biopsy<br/>Cytosine Deaminase<br/>DNA, Viral--blood<br/>Flucytosine--pharmacokinetics<br/>Ganciclovir--pharmacokinetics<br/>Genetic Therapy--adverse effects<br/>Herpesvirus 1, Human--enzymology<br/>Humans<br/>Male<br/>Middle Aged<br/>Neoplasm Recurrence, Local--blood<br/>Nucleoside Deaminases--genetics<br/>Prodrugs--pharmacokinetics<br/>Prostate-Specific Antigen--blood<br/>Prostatic Neoplasms--blood<br/>Thymidine Kinase--genetics<br/>Virus Replication<br/>Virus Shedding