TY  - GEN
AU  - Welcher,Brent C
AU  - Carra,John H
AU  - DaSilva,Luis
AU  - Hanson,Juli
AU  - David,Chella S
AU  - Aman,M Javad
AU  - Bavari,Sina
TI  - Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics
SN  - 0022-1899
PY  - 2002///0917
KW  - Animals
KW  - Bacterial Proteins
KW  - CD4 Antigens
KW  - genetics
KW  - Cytokines
KW  - blood
KW  - Disease Models, Animal
KW  - Exotoxins
KW  - HLA-DQ Antigens
KW  - Humans
KW  - Liver
KW  - enzymology
KW  - Membrane Proteins
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Receptors, Antigen, T-Cell, alpha-beta
KW  - metabolism
KW  - Shock, Septic
KW  - etiology
KW  - Streptococcal Infections
KW  - Streptococcal Vaccines
KW  - administration & dosage
KW  - Streptococcus pyogenes
KW  - immunology
KW  - Superantigens
KW  - T-Lymphocytes
KW  - Transgenes
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1086/341828
ER  -