TY  - GEN
AU  - Kurata,Yasuo
AU  - Ieiri,Ichiro
AU  - Kimura,Miyuki
AU  - Morita,Toshihiro
AU  - Irie,Shin
AU  - Urae,Akinori
AU  - Ohdo,Shigehiro
AU  - Ohtani,Hisakazu
AU  - Sawada,Yasufumi
AU  - Higuchi,Shun
AU  - Otsubo,Kenji
TI  - Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
SN  - 0009-9236
PY  - 2002///0916
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - metabolism
KW  - Administration, Oral
KW  - Adult
KW  - Alleles
KW  - Anti-Bacterial Agents
KW  - pharmacokinetics
KW  - Area Under Curve
KW  - Asian People
KW  - genetics
KW  - Biological Availability
KW  - Cardiotonic Agents
KW  - Clarithromycin
KW  - administration & dosage
KW  - Cytochrome P-450 Enzyme System
KW  - Digoxin
KW  - Drug Administration Schedule
KW  - Drug Interactions
KW  - Enzyme Inhibitors
KW  - Genes, MDR
KW  - Genotype
KW  - Humans
KW  - Injections, Intravenous
KW  - Japan
KW  - Male
KW  - Polymerase Chain Reaction
KW  - Polymorphism, Genetic
KW  - Polymorphism, Restriction Fragment Length
KW  - Reference Values
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1067/mcp.2002.126177
ER  -