TY - GEN AU - Mansky,Louis M AU - Pearl,Dennis K AU - Gajary,Lisa C TI - Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies SN - 0022-538X PY - 2002///1002 KW - Animals KW - Anti-HIV Agents KW - pharmacology KW - COS Cells KW - Dose-Response Relationship, Drug KW - Drug Resistance, Viral KW - genetics KW - Genetic Vectors KW - HIV Reverse Transcriptase KW - metabolism KW - HIV-1 KW - drug effects KW - HeLa Cells KW - Humans KW - Hydroxyurea KW - Lamivudine KW - Mutation KW - Reverse Transcriptase Inhibitors KW - Thymidine KW - Virus Replication KW - Zidovudine N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1128/jvi.76.18.9253-9259.2002 ER -