Hetian, Lei

A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor. [electronic resource] - The Journal of biological chemistry Nov 2002 - 43137-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M203103200 doi


Allantois--drug effects
Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Breast Neoplasms
Cell Division
Cells, Cultured
Chick Embryo
Chorion--drug effects
DNA Primers
DNA, Complementary
Endothelial Growth Factors--pharmacology
Endothelium, Vascular--cytology
Female
Humans
Intercellular Signaling Peptides and Proteins--pharmacology
Lymphokines--pharmacology
Neoplasm Metastasis--prevention & control
Neovascularization, Pathologic--prevention & control
Neovascularization, Physiologic--drug effects
Oligopeptides--chemistry
Peptide Fragments--chemistry
Peptide Library
Protein-Tyrosine Kinases--metabolism
Recombinant Proteins--pharmacology
Reverse Transcriptase Polymerase Chain Reaction
Substrate Specificity
Tumor Cells, Cultured
Umbilical Veins
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors
Vascular Endothelial Growth Factors