TY - GEN AU - McLean,Alison J AU - Zeng,Fu-Yue AU - Behan,Dominic AU - Chalmers,Derek AU - Milligan,Graeme TI - Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor SN - 0026-895X PY - 2002///0905 KW - Adrenergic beta-Antagonists KW - pharmacology KW - Betaxolol KW - GTP-Binding Protein alpha Subunits, Gs KW - metabolism KW - Guanine Nucleotides KW - Guanosine 5'-O-(3-Thiotriphosphate) KW - Humans KW - Mutation KW - Receptors, Adrenergic, beta-1 KW - genetics KW - Sulfur Radioisotopes KW - Transfection KW - Up-Regulation N1 - Publication Type: Journal Article UR - https://doi.org/10.1124/mol.62.3.747 ER -