TY - GEN AU - Basso,Andrea D AU - Solit,David B AU - Chiosis,Gabriela AU - Giri,Banabihari AU - Tsichlis,Philip AU - Rosen,Neal TI - Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function SN - 0021-9258 PY - 2002///1219 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - Adenosine Triphosphate KW - metabolism KW - Animals KW - Cell Cycle Proteins KW - Chaperonins KW - Cyclic AMP-Dependent Protein Kinases KW - Cysteine Endopeptidases KW - Down-Regulation KW - Drosophila Proteins KW - Female KW - HSP90 Heat-Shock Proteins KW - Humans KW - Immunoblotting KW - Mice KW - Mice, Inbred BALB C KW - Microscopy, Fluorescence KW - Molecular Chaperones KW - Multienzyme Complexes KW - Phosphorylation KW - Proteasome Endopeptidase Complex KW - Protein Binding KW - Protein Serine-Threonine Kinases KW - Protein Structure, Tertiary KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Time Factors KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M206322200 ER -