TY - GEN AU - Gomtsyan,Arthur AU - Didomenico,Stanley AU - Lee,Chih-Hung AU - Matulenko,Mark A AU - Kim,Ki AU - Kowaluk,Elizabeth A AU - Wismer,Carol T AU - Mikusa,Joe AU - Yu,Haixia AU - Kohlhaas,Kathy AU - Jarvis,Michael F AU - Bhagwat,Shripad S TI - Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors SN - 0022-2623 PY - 2002///0904 KW - Adenosine KW - metabolism KW - Adenosine Kinase KW - antagonists & inhibitors KW - Analgesics KW - chemical synthesis KW - Animals KW - Anti-Inflammatory Agents KW - Enzyme Inhibitors KW - Humans KW - Magnetic Resonance Spectroscopy KW - Models, Molecular KW - Morpholines KW - Pain Measurement KW - Phosphorylation KW - Pyridines KW - Pyrimidines KW - Rats KW - Structure-Activity Relationship KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm020049a ER -