Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. [electronic resource]
- Blood Aug 2002
- 1294-301 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-4971
Animals Apoptosis--radiation effects B-Lymphocytes--metabolism Cell Death--radiation effects Cell Line Ceramides--metabolism Cobalt Radioisotopes DNA Repair--drug effects Enzyme Inhibitors--pharmacology Estrenes--pharmacology Gene Expression Humans Indoles Isoenzymes--antagonists & inhibitors Kinetics Mice Microscopy, Fluorescence Phosphatidylinositol 3-Kinases--metabolism Phospholipase C gamma Proto-Oncogene Proteins c-kit--genetics Pyrrolidinones--pharmacology Radiation-Protective Agents Signal Transduction Sphingomyelin Phosphodiesterase--metabolism Sphingomyelins--metabolism Stem Cell Factor--pharmacology Transfection Type C Phospholipases--antagonists & inhibitors