TY  - GEN
AU  - Kaether,Christoph
AU  - Lammich,Sven
AU  - Edbauer,Dieter
AU  - Ertl,Michaela
AU  - Rietdorf,Jens
AU  - Capell,Anja
AU  - Steiner,Harald
AU  - Haass,Christian
TI  - Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane
SN  - 0021-9525
PY  - 2002///0909
KW  - Alzheimer Disease
KW  - genetics
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Peptides
KW  - biosynthesis
KW  - Amyloid beta-Protein Precursor
KW  - metabolism
KW  - Aspartic Acid
KW  - Aspartic Acid Endopeptidases
KW  - Cell Compartmentation
KW  - physiology
KW  - Cell Membrane
KW  - Cells, Cultured
KW  - Endocytosis
KW  - Endopeptidases
KW  - drug effects
KW  - Eukaryotic Cells
KW  - Green Fluorescent Proteins
KW  - Humans
KW  - Indicators and Reagents
KW  - Luminescent Proteins
KW  - Macromolecular Substances
KW  - Membrane Glycoproteins
KW  - Membrane Proteins
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Presenilin-1
KW  - Protein Binding
KW  - Protein Transport
KW  - Receptors, Notch
KW  - Recombinant Fusion Proteins
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1083/jcb.200201123
ER  -