TY - GEN AU - Drevs,Joachim AU - Müller-Driver,Ralph AU - Wittig,Christine AU - Fuxius,Stefan AU - Esser,Norbert AU - Hugenschmidt,Harald AU - Konerding,Moritz A AU - Allegrini,Peter R AU - Wood,Jeanette AU - Hennig,Jürgen AU - Unger,Clemens AU - Marmé,Dieter TI - PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging SN - 0008-5472 PY - 2002///0813 KW - Angiogenesis Inhibitors KW - pharmacology KW - Animals KW - Benzimidazoles KW - metabolism KW - Blood Vessels KW - anatomy & histology KW - Capillary Permeability KW - drug effects KW - Carcinoma, Renal Cell KW - blood supply KW - Enzyme Inhibitors KW - Extravasation of Diagnostic and Therapeutic Materials KW - Female KW - Fluorescent Dyes KW - Heterocyclic Compounds KW - blood KW - Kidney Neoplasms KW - Magnetic Resonance Angiography KW - Mice KW - Mice, Inbred BALB C KW - Neovascularization, Pathologic KW - drug therapy KW - Organometallic Compounds KW - Phthalazines KW - Pyridines KW - Receptor Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Receptors, Growth Factor KW - Receptors, Vascular Endothelial Growth Factor KW - Regional Blood Flow N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -