Drevs, Joachim <br/><br/>
PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging.  [electronic resource] 

 -  Cancer research  Jul 2002 
 - 4015-22 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Angiogenesis Inhibitors--pharmacology<br/>Animals<br/>Benzimidazoles--metabolism<br/>Blood Vessels--anatomy & histology<br/>Capillary Permeability--drug effects<br/>Carcinoma, Renal Cell--blood supply<br/>Enzyme Inhibitors--pharmacology<br/>Extravasation of Diagnostic and Therapeutic Materials<br/>Female<br/>Fluorescent Dyes--metabolism<br/>Heterocyclic Compounds--blood<br/>Kidney Neoplasms--blood supply<br/>Magnetic Resonance Angiography<br/>Mice<br/>Mice, Inbred BALB C<br/>Neovascularization, Pathologic--drug therapy<br/>Organometallic Compounds--blood<br/>Phthalazines--pharmacology<br/>Pyridines<br/>Receptor Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Receptors, Growth Factor--antagonists & inhibitors<br/>Receptors, Vascular Endothelial Growth Factor<br/>Regional Blood Flow--drug effects