TY - GEN AU - Kelly,Louise M AU - Yu,Jin-Chen AU - Boulton,Christina L AU - Apatira,Mutiah AU - Li,Jason AU - Sullivan,Carol M AU - Williams,Ifor AU - Amaral,Sonia M AU - Curley,David P AU - Duclos,Nicole AU - Neuberg,Donna AU - Scarborough,Robert M AU - Pandey,Anjali AU - Hollenbach,Stanley AU - Abe,Keith AU - Lokker,Nathalie A AU - Gilliland,D Gary AU - Giese,Neill A TI - CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML) SN - 1535-6108 PY - 2002///0927 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Bone Marrow Cells KW - enzymology KW - Bone Marrow Transplantation KW - Enzyme Inhibitors KW - Flow Cytometry KW - Humans KW - Immunoblotting KW - Interleukin-3 KW - metabolism KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Mutation KW - Phosphorylation KW - Piperazines KW - Proto-Oncogene Proteins KW - antagonists & inhibitors KW - Proto-Oncogene Proteins c-kit KW - Quinazolines KW - Receptor Protein-Tyrosine Kinases KW - Receptors, Cell Surface KW - Receptors, Platelet-Derived Growth Factor KW - Tandem Repeat Sequences KW - Transfection KW - Tumor Cells, Cultured KW - fms-Like Tyrosine Kinase 3 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s1535-6108(02)00070-3 ER -