Kelly, Louise M
CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). [electronic resource]
- Cancer cell Jun 2002
- 421-32 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
ISSN: 1535-6108
Standard No.: 10.1016/s1535-6108(02)00070-3 doi
Subjects--Topical Terms: Animals Antineoplastic Agents--pharmacology Apoptosis--drug effects Bone Marrow Cells--enzymology Bone Marrow Transplantation Enzyme Inhibitors--pharmacology Flow Cytometry Humans Immunoblotting Interleukin-3--metabolism Leukemia, Myeloid, Acute--drug therapy Mice Mice, Inbred BALB C Mice, Nude Mutation Phosphorylation Piperazines--pharmacology Proto-Oncogene Proteins--antagonists & inhibitors Proto-Oncogene Proteins c-kit--drug effects Quinazolines--pharmacology Receptor Protein-Tyrosine Kinases--antagonists & inhibitors Receptors, Cell Surface--antagonists & inhibitors Receptors, Platelet-Derived Growth Factor--antagonists & inhibitors Tandem Repeat Sequences Transfection Tumor Cells, Cultured--drug effects fms-Like Tyrosine Kinase 3