TY  - GEN
AU  - Le Jeune,Ivan R
AU  - Shepherd,Malcolm
AU  - Van Heeke,Gino
AU  - Houslay,Miles D
AU  - Hall,Ian P
TI  - Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter
SN  - 0021-9258
PY  - 2002///1113
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - metabolism
KW  - 8-Bromo Cyclic Adenosine Monophosphate
KW  - Alternative Splicing
KW  - Animals
KW  - Base Sequence
KW  - CHO Cells
KW  - Chromosomes, Human, Pair 5
KW  - Cricetinae
KW  - Culture Media, Serum-Free
KW  - pharmacology
KW  - Cyclic AMP
KW  - Cyclic Nucleotide Phosphodiesterases, Type 3
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - Down-Regulation
KW  - Genes, Reporter
KW  - Humans
KW  - Kinetics
KW  - Luciferases
KW  - Models, Genetic
KW  - Molecular Sequence Data
KW  - Muscle, Smooth
KW  - cytology
KW  - Mutagenesis, Site-Directed
KW  - Phosphoric Diester Hydrolases
KW  - biosynthesis
KW  - Precipitin Tests
KW  - Promoter Regions, Genetic
KW  - Protein Isoforms
KW  - Protein Structure, Tertiary
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Trachea
KW  - Transcription, Genetic
KW  - Transfection
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M204832200
ER  -