TY - GEN AU - MacKeigan,Jeffrey P AU - Taxman,Debra J AU - Hunter,Deborah AU - Earp,H Shelton AU - Graves,Lee M AU - Ting,Jenny P-Y TI - Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition SN - 1078-0432 PY - 2003///0121 KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Northern KW - Butadienes KW - Chromones KW - Drug Therapy, Combination KW - Enzyme Inhibitors KW - Epidermal Growth Factor KW - Humans KW - Immunoblotting KW - MAP Kinase Signaling System KW - Mitogen-Activated Protein Kinase Kinases KW - antagonists & inhibitors KW - Morpholines KW - Neuregulin-1 KW - Nitriles KW - Paclitaxel KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Plasmids KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - RNA, Messenger KW - metabolism KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -