TY - GEN AU - Connolly,E M AU - Harmey,J H AU - O'Grady,T AU - Foley,D AU - Roche-Nagle,G AU - Kay,E AU - Bouchier-Hayes,D J TI - Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer SN - 0007-0920 PY - 2002///0830 KW - Adenocarcinoma KW - blood supply KW - Angiogenesis Inhibitors KW - pharmacology KW - Animals KW - Apoptosis KW - drug effects KW - Cyclooxygenase 1 KW - Cyclooxygenase 2 KW - Cyclooxygenase 2 Inhibitors KW - Cyclooxygenase Inhibitors KW - Drug Screening Assays, Antitumor KW - Endothelial Growth Factors KW - biosynthesis KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Indomethacin KW - Isoenzymes KW - antagonists & inhibitors KW - Lung Neoplasms KW - drug therapy KW - Lymphokines KW - Mammary Neoplasms, Experimental KW - Membrane Proteins KW - Mice KW - Mice, Inbred BALB C KW - Neoplasm Proteins KW - Neoplasm Transplantation KW - Neovascularization, Pathologic KW - Prostaglandin-Endoperoxide Synthases KW - Pyrazoles KW - Random Allocation KW - Substrate Specificity KW - Sulfonamides KW - Tumor Cells, Cultured KW - enzymology KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factors N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/sj.bjc.6600462 ER -