TY  - GEN
AU  - Daigo,Satoshi
AU  - Takahashi,Yoshiki
AU  - Fujieda,Masaki
AU  - Ariyoshi,Noritaka
AU  - Yamazaki,Hiroshi
AU  - Koizumi,Wasaburo
AU  - Tanabe,Satoshi
AU  - Saigenji,Katsunori
AU  - Nagayama,Sekio
AU  - Ikeda,Kazumasa
AU  - Nishioka,Yasuhiko
AU  - Kamataki,Tetsuya
TI  - A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur
SN  - 0960-314X
PY  - 2002///1107
KW  - Administration, Oral
KW  - Antimetabolites, Antineoplastic
KW  - administration & dosage
KW  - Area Under Curve
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Coumarins
KW  - metabolism
KW  - Cytochrome P-450 CYP2A6
KW  - DNA Primers
KW  - chemistry
KW  - DNA, Neoplasm
KW  - blood
KW  - Drug Combinations
KW  - Escherichia coli
KW  - Genotype
KW  - Humans
KW  - Kinetics
KW  - Middle Aged
KW  - Mixed Function Oxygenases
KW  - Mutagenesis, Site-Directed
KW  - Oxonic Acid
KW  - Polymerase Chain Reaction
KW  - Polymorphism, Genetic
KW  - Pyridines
KW  - Recombinant Proteins
KW  - isolation & purification
KW  - Stomach Neoplasms
KW  - enzymology
KW  - Tegafur
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1097/00008571-200206000-00005
ER  -