Daigo, Satoshi <br/><br/>
A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur.  [electronic resource] 

 -  Pharmacogenetics  Jun 2002 
 - 299-306 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0960-314X 
<br/><br/><label>Standard No.: </label>10.1097/00008571-200206000-00005  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Antimetabolites, Antineoplastic--administration & dosage<br/>Area Under Curve<br/>Aryl Hydrocarbon Hydroxylases--genetics<br/>Coumarins--metabolism<br/>Cytochrome P-450 CYP2A6<br/>DNA Primers--chemistry<br/>DNA, Neoplasm--blood<br/>Drug Combinations<br/>Escherichia coli<br/>Genotype<br/>Humans<br/>Kinetics<br/>Middle Aged<br/>Mixed Function Oxygenases--genetics<br/>Mutagenesis, Site-Directed<br/>Oxonic Acid--administration & dosage<br/>Polymerase Chain Reaction<br/>Polymorphism, Genetic<br/>Pyridines--administration & dosage<br/>Recombinant Proteins--isolation & purification<br/>Stomach Neoplasms--enzymology<br/>Tegafur--administration & dosage<br/>Transfection