TY - GEN AU - Hantgan,Roy R AU - Stahle,Mary C AU - Jerome,W Gray AU - Nagaswami,Chandrasekaran AU - Weisel,John W TI - Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure SN - 0340-6245 PY - 2002///0909 KW - Adult KW - Circular Dichroism KW - Dose-Response Relationship, Drug KW - Fibrin KW - metabolism KW - Humans KW - Microscopy, Electron KW - Nephelometry and Turbidimetry KW - Platelet Adhesiveness KW - drug effects KW - Platelet Aggregation Inhibitors KW - administration & dosage KW - Platelet Glycoprotein GPIIb-IIIa Complex KW - chemistry KW - Protein Conformation KW - Protein Interaction Mapping KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Protein Subunits KW - Receptor Aggregation KW - Tirofiban KW - Tyrosine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -