Glucose desensitization in INS-1 cells: evidence of impaired function caused by glucose metabolite(s) rather than by the glucose molecule per se. [electronic resource]
- Metabolism: clinical and experimental Jun 2002
- 671-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0026-0495
10.1053/meta.2002.32722 doi
Animals Cell Line Deoxyglucose--pharmacology Dose-Response Relationship, Drug Drug Tolerance--physiology Enzyme Inhibitors--pharmacology Glucokinase--antagonists & inhibitors Glucose--metabolism Glucose-6-Phosphate Isomerase--antagonists & inhibitors Glyceraldehyde--pharmacology Insulin--genetics Insulin Secretion Intracellular Fluid--metabolism Islets of Langerhans--drug effects Mannoheptulose--pharmacology RNA, Messenger--metabolism Rats Time Factors