TY  - GEN
AU  - Villhauer,Edwin B
AU  - Brinkman,John A
AU  - Naderi,Goli B
AU  - Dunning,Beth E
AU  - Mangold,Bonnie L
AU  - Mone,Manisha D
AU  - Russell,Mary E
AU  - Weldon,Stephen C
AU  - Hughes,Thomas E
TI  - 1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
SN  - 0022-2623
PY  - 2002///0627
KW  - Administration, Oral
KW  - Animals
KW  - Biological Availability
KW  - Caco-2 Cells
KW  - Dipeptidyl Peptidase 4
KW  - metabolism
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Glucose Tolerance Test
KW  - Humans
KW  - Hypolipidemic Agents
KW  - Macaca fascicularis
KW  - Male
KW  - Nitriles
KW  - Protease Inhibitors
KW  - Pyrrolidines
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm025522z
ER  -