TY  - GEN
AU  - Granvil,Camille P
AU  - Krausz,Kristopher W
AU  - Gelboin,Harry V
AU  - Idle,Jeffrey R
AU  - Gonzalez,Frank J
TI  - 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine
SN  - 0022-3565
PY  - 2002///0619
KW  - Adrenergic Agents
KW  - chemistry
KW  - Antimalarials
KW  - pharmacology
KW  - Cytochrome P-450 CYP1A1
KW  - metabolism
KW  - Cytochrome P-450 CYP2D6
KW  - Cytochrome P-450 CYP2D6 Inhibitors
KW  - Debrisoquin
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Hydroxylation
KW  - drug effects
KW  - Microsomes
KW  - Quinidine
KW  - Quinine
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/jpet.301.3.1025
ER  -