Graichen, Ralph

Autocrine human growth hormone inhibits placental transforming growth factor-beta gene transcription to prevent apoptosis and allow cell cycle progression of human mammary carcinoma cells. [electronic resource] - The Journal of biological chemistry Jul 2002 - 26662-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M109931200 doi


Apoptosis--drug effects
Binding Sites
Blotting, Northern
Breast Neoplasms--pathology
Cell Cycle--drug effects
Cyclin D1--biosynthesis
Female
Genes, Reporter
Growth Substances--genetics
Human Growth Hormone--pharmacology
Humans
Insulin-Like Growth Factor I--metabolism
Luciferases--metabolism
Oligonucleotides, Antisense--metabolism
Plasmids
Pregnancy Proteins--genetics
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic--drug effects
Tumor Cells, Cultured
Tumor Suppressor Protein p53--metabolism