Liu, Jian-Ning <br/><br/>
Prourokinase mutant that induces highly effective clot lysis without interfering with hemostasis.  [electronic resource] 

 -  Circulation research  Apr 2002 
 - 757-63 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1524-4571 
<br/><br/><label>Standard No.: </label>10.1161/01.res.0000014825.71092.bd  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Substitution<br/>Animals<br/>Bleeding Time<br/>Blood Coagulation--drug effects<br/>Disease Models, Animal<br/>Dogs<br/>Drug Evaluation, Preclinical<br/>Drug Stability<br/>Enzyme Activation--drug effects<br/>Femoral Vein--drug effects<br/>Fibrin--drug effects<br/>Fibrinolysis--drug effects<br/>Hemorrhage--prevention & control<br/>Hemostasis--drug effects<br/>Humans<br/>Macaca mulatta<br/>Male<br/>Mutagenesis, Site-Directed<br/>Plasma--drug effects<br/>Plasminogen--drug effects<br/>Recombinant Proteins--genetics<br/>Thrombolytic Therapy--methods<br/>Thrombosis--drug therapy<br/>Tissue Plasminogen Activator--pharmacology<br/>Urokinase-Type Plasminogen Activator--genetics