Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI). [electronic resource]
- Carcinogenesis Apr 2002
- 587-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0143-3334
10.1093/carcin/23.4.587 doi
Animals Apoptosis Carcinogens, Environmental Caspase 6 Caspases--biosynthesis Chromates--pharmacology Chromium--administration & dosage DNA Topoisomerases, Type II--biosynthesis DNA, Complementary--metabolism DNA-Binding Proteins Deoxyribonuclease I--biosynthesis Dose-Response Relationship, Drug In Situ Nick-End Labeling JNK Mitogen-Activated Protein Kinases Liver--drug effects Lung--drug effects Male Mitogen-Activated Protein Kinases--biosynthesis Nuclear Proteins Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins--biosynthesis Proto-Oncogene Proteins c-bcl-2 Proto-Oncogene Proteins c-mdm2 Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction Time Factors Trachea--metabolism bcl-2-Associated X Protein