Hauel, Norbert H <br/><br/>
Structure-based design of novel potent nonpeptide thrombin inhibitors.  [electronic resource] 

 -  Journal of medicinal chemistry  Apr 2002 
 - 1757-66 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0109513  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Benzimidazoles--chemical synthesis<br/>Cattle<br/>Crystallography, X-Ray<br/>Dabigatran<br/>Drug Evaluation, Preclinical<br/>Fibrinolytic Agents--chemical synthesis<br/>Humans<br/>Macaca mulatta<br/>Models, Molecular<br/>Partial Thromboplastin Time<br/>Prodrugs--chemical synthesis<br/>Protein Binding<br/>Pyridines--chemical synthesis<br/>Rats<br/>Serine Proteinase Inhibitors--chemical synthesis<br/>Structure-Activity Relationship<br/>Thrombin--antagonists & inhibitors