TY - GEN AU - Hartley,David AU - Cooper,Geoffrey M TI - Role of mTOR in the degradation of IRS-1: regulation of PP2A activity SN - 0730-2312 PY - 2002///0722 KW - 3T3 Cells KW - drug effects KW - Adipocytes KW - metabolism KW - Animals KW - Antibiotics, Antineoplastic KW - pharmacology KW - Becaplermin KW - Electrophoretic Mobility Shift Assay KW - Enzyme Inhibitors KW - Fibroblasts KW - Hypoglycemic Agents KW - Immunoblotting KW - Insulin KW - Insulin Receptor Substrate Proteins KW - Mice KW - Okadaic Acid KW - Phosphoprotein Phosphatases KW - antagonists & inhibitors KW - Phosphoproteins KW - genetics KW - Platelet-Derived Growth Factor KW - Protein Kinases KW - physiology KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-sis KW - Ribosomal Protein S6 Kinases KW - Sirolimus KW - TOR Serine-Threonine Kinases N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1002/jcb.10135 ER -