Siggelkow, Heide <br/><br/>
Prolonged culture of HOS 58 human osteosarcoma cells with 1,25-(OH)2-D3, TGF-beta, and dexamethasone reveals physiological regulation of alkaline phosphatase, dissociated osteocalcin gene expression, and protein synthesis and lack of mineralization.  [electronic resource] 

 -  Journal of cellular biochemistry  2002 
 - 279-94 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0730-2312 
<br/><br/><label>Standard No.: </label>10.1002/jcb.10122  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Alkaline Phosphatase--genetics<br/>Animals<br/>Blotting, Northern<br/>Calcification, Physiologic<br/>Calcitriol--pharmacology<br/>Collagen Type I--genetics<br/>Core Binding Factor alpha Subunits<br/>DNA Primers--chemistry<br/>DNA-Binding Proteins--metabolism<br/>Dexamethasone--pharmacology<br/>Gene Expression<br/>Gene Expression Regulation, Enzymologic<br/>Humans<br/>Male<br/>Mice<br/>Microscopy, Electron, Scanning<br/>Osteocalcin--genetics<br/>Osteosarcoma--drug therapy<br/>RNA, Messenger--metabolism<br/>Rats<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Transcription Factors--metabolism<br/>Transforming Growth Factor beta--pharmacology<br/>Tumor Cells, Cultured--drug effects