TY - GEN AU - Ventura,Andrea AU - Luzi,Lucilla AU - Pacini,Sonia AU - Baldari,Cosima T AU - Pelicci,Pier Giuseppe TI - The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter SN - 0021-9258 PY - 2002///0719 KW - 3T3 Cells KW - Adaptor Proteins, Signal Transducing KW - Adaptor Proteins, Vesicular Transport KW - Animals KW - Base Sequence KW - Cell Line KW - Cell Lineage KW - Cytosine KW - metabolism KW - Gene Silencing KW - Histone Deacetylases KW - Histones KW - Humans KW - Hydroxamic Acids KW - pharmacology KW - Luciferases KW - Methylation KW - Mice KW - Models, Genetic KW - Molecular Sequence Data KW - Plasmids KW - Promoter Regions, Genetic KW - Protein Isoforms KW - Protein Structure, Tertiary KW - Proteins KW - genetics KW - RNA, Messenger KW - Reverse Transcriptase Polymerase Chain Reaction KW - Ribonucleases KW - Shc Signaling Adaptor Proteins KW - Src Homology 2 Domain-Containing, Transforming Protein 1 KW - Time Factors KW - Transcription, Genetic KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M200280200 ER -