Biessen, Erik A L

Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes. [electronic resource] - Bioconjugate chemistry - 295-302 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1043-1802

10.1021/bc015550g doi


Animals
Asialoglycoproteins--pharmacology
Base Sequence
Biological Transport--drug effects
Carrier Proteins--genetics
Cells, Cultured
Drug Delivery Systems
Drug Design
Fetuins
Gene Expression Regulation--drug effects
Hepatocytes--drug effects
Humans
Kinetics
Mice
Mice, Inbred C57BL
Microsomes, Liver--drug effects
Molecular Structure
Peptide Nucleic Acids--chemical synthesis
Prodrugs--chemical synthesis
RNA, Messenger--genetics
Tumor Cells, Cultured
alpha-Fetoproteins--pharmacology