TY - GEN AU - Liu,Dongbo AU - Cardozo,Alessandra K AU - Darville,Martine I AU - Eizirik,Décio L TI - Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus SN - 0013-7227 PY - 2002///0429 KW - Adenoviridae Infections KW - pathology KW - Animals KW - Apoptosis KW - physiology KW - Cell Death KW - drug effects KW - Cells, Cultured KW - Chemokines KW - biosynthesis KW - Cytokines KW - Diabetes Mellitus, Type 1 KW - physiopathology KW - Fas Ligand Protein KW - Insulin KW - Interferon-gamma KW - pharmacology KW - Interleukin-1 KW - Islets of Langerhans KW - Luciferases KW - metabolism KW - Male KW - Membrane Glycoproteins KW - NF-kappa B KW - Poly I-C KW - RNA, Double-Stranded KW - RNA, Messenger KW - Rats KW - Rats, Wistar KW - Reverse Transcriptase Polymerase Chain Reaction KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1210/endo.143.4.8737 ER -