TY  - GEN
AU  - Amtul,Zareen
AU  - Lewis,Patrick A
AU  - Piper,Sian
AU  - Crook,Richard
AU  - Baker,Matt
AU  - Findlay,Kirk
AU  - Singleton,Andrew
AU  - Hogg,Marion
AU  - Younkin,Linda
AU  - Younkin,Steven G
AU  - Hardy,John
AU  - Hutton,Michael
AU  - Boeve,Bradley F
AU  - Tang-Wai,David
AU  - Golde,Todd E
TI  - A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch
SN  - 0969-9961
PY  - 2002///0509
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Protein Precursor
KW  - metabolism
KW  - Animals
KW  - CHO Cells
KW  - Cricetinae
KW  - Dementia
KW  - genetics
KW  - Endopeptidases
KW  - Glioma
KW  - Membrane Proteins
KW  - Mutation
KW  - Phenotype
KW  - Presenilin-1
KW  - Receptors, Notch
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/nbdi.2001.0473
ER  -