TY - GEN AU - Connolly,Stephen AU - Bennion,Colin AU - Botterell,Sarah AU - Croshaw,Pamela J AU - Hallam,Catherine AU - Hardy,Kim AU - Hartopp,Paul AU - Jackson,Clive G AU - King,Sarah J AU - Lawrence,Louise AU - Mete,Antonio AU - Murray,David AU - Robinson,David H AU - Smith,Gillian M AU - Stein,Linda AU - Walters,Iain AU - Wells,Edward AU - Withnall,W John TI - Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton SN - 0022-2623 PY - 2002///0426 KW - Arachidonic Acid KW - analysis KW - Cytosol KW - enzymology KW - Drug Design KW - Enzyme Inhibitors KW - chemical synthesis KW - HL-60 Cells KW - drug effects KW - Humans KW - Ketones KW - Lipid Bilayers KW - metabolism KW - Phospholipases A KW - antagonists & inhibitors KW - Propane KW - analogs & derivatives KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm011050x ER -