Connolly, Stephen <br/><br/>
Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2002 
 - 1348-62 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm011050x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Arachidonic Acid--analysis<br/>Cytosol--enzymology<br/>Drug Design<br/>Enzyme Inhibitors--chemical synthesis<br/>HL-60 Cells--drug effects<br/>Humans<br/>Ketones--chemical synthesis<br/>Lipid Bilayers--metabolism<br/>Phospholipases A--antagonists & inhibitors<br/>Propane--analogs & derivatives<br/>Structure-Activity Relationship