TY - GEN AU - Zollner,Thomas M AU - Podda,Maurizio AU - Pien,Christine AU - Elliott,Peter J AU - Kaufmann,Roland AU - Boehncke,Wolf-Henning TI - Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model SN - 0021-9738 PY - 2002///0403 KW - Acetylcysteine KW - analogs & derivatives KW - Animals KW - Antigens, CD KW - metabolism KW - Antigens, Differentiation, T-Lymphocyte KW - Bacterial Toxins KW - Cysteine Endopeptidases KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - DNA KW - drug effects KW - Disease Models, Animal KW - Enterotoxins KW - immunology KW - HLA-DR Antigens KW - Humans KW - Lectins, C-Type KW - Lymphocyte Activation KW - Mice KW - Mice, SCID KW - Multienzyme Complexes KW - antagonists & inhibitors KW - NF-kappa B KW - Proteasome Endopeptidase Complex KW - Psoriasis KW - drug therapy KW - Receptors, Interleukin-2 KW - Skin Transplantation KW - Superantigens KW - T-Lymphocytes KW - Transplantation, Heterologous N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI12736 ER -