TY - GEN AU - Hansen,William J AU - Ohh,Michael AU - Moslehi,Javid AU - Kondo,Keiichi AU - Kaelin,William G AU - Welch,William J TI - Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity SN - 0270-7306 PY - 2002///0312 KW - Carcinoma, Renal Cell KW - genetics KW - Cell Cycle Proteins KW - metabolism KW - Chaperonin Containing TCP-1 KW - Chaperonins KW - Cullin Proteins KW - Elongin KW - Exons KW - physiology KW - Humans KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Ligases KW - Macromolecular Substances KW - Mutagenesis, Site-Directed KW - Mutation KW - Protein Binding KW - drug effects KW - Protein Folding KW - Structure-Activity Relationship KW - Transcription Factors KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Suppressor Proteins KW - Ubiquitin KW - Ubiquitin-Protein Ligases KW - Von Hippel-Lindau Tumor Suppressor Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1128/MCB.22.6.1947-1960.2002 ER -