The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. [electronic resource]
- The Journal of biological chemistry May 2002
- 16547-52 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M110629200 doi
Androstadienes--pharmacology Animals Apoptosis Blotting, Western Cell Line Cell Survival Cells, Cultured Chloride Channels--antagonists & inhibitors Cycloheximide--pharmacology Cytochrome c Group--metabolism Cytosol--metabolism DNA Damage Diuretics--pharmacology Enzyme Inhibitors--pharmacology Etoposide--pharmacology Fibroblasts--drug effects Furosemide--pharmacology Mice Mitochondria--metabolism Nucleic Acid Synthesis Inhibitors--pharmacology Phosphorylation Protein Synthesis Inhibitors--pharmacology Protein Transport Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-bcl-2--metabolism Proto-Oncogene Proteins c-myc--metabolism Time Factors Transfection Tumor Suppressor Protein p53--metabolism Ubiquinone--analogs & derivatives Up-Regulation Wortmannin bcl-2-Associated X Protein