TY  - GEN
AU  - Sugihara,Nobuhiro
AU  - Ise,Hirohiko
AU  - Negishi,Naoki
AU  - Nikaido,Toshio
AU  - Akaike,Toshihiro
TI  - Drug metabolic activity of cultured hepatocytes can synchronize with bile acid concentration in the medium
SN  - 0263-6484
PY  - 2002///0510
KW  - Aminopyrine N-Demethylase
KW  - metabolism
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Bile Acids and Salts
KW  - Biological Clocks
KW  - Cells, Cultured
KW  - Culture Media
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - Glycocholic Acid
KW  - pharmacology
KW  - Hepatocytes
KW  - drug effects
KW  - Kinetics
KW  - Male
KW  - Mice
KW  - Mice, Inbred ICR
KW  - Oxidoreductases, N-Demethylating
KW  - RNA, Messenger
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/cbf.933
ER  -