Kusama, Toshiyuki

3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. [electronic resource] - Gastroenterology Feb 2002 - 308-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0016-5085

10.1053/gast.2002.31093 doi


Adenocarcinoma--drug therapy
Animals
Cell Division--drug effects
Cell Membrane--metabolism
Cytosol--metabolism
Epidermal Growth Factor--pharmacology
Fatty Acids, Monounsaturated--pharmacology
Fluvastatin
Humans
Hydroxymethylglutaryl CoA Reductases--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Hypercholesterolemia--drug therapy
Indoles--pharmacology
Liver Neoplasms, Experimental--drug therapy
Lovastatin--pharmacology
Mice
Mice, Nude
Neoplasm Invasiveness
Pancreatic Neoplasms--drug therapy
Tumor Cells, Cultured
rhoA GTP-Binding Protein--metabolism