TY - GEN AU - Kang,Dongmin AU - Chen,James AU - Wong,Jim AU - Fang,Guowei TI - The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition SN - 0021-9525 PY - 2002///0328 KW - Animals KW - Blotting, Western KW - CDC2 Protein Kinase KW - antagonists & inhibitors KW - Cell Cycle Proteins KW - chemistry KW - Cell Line KW - Cell-Free System KW - Enzyme Activation KW - G2 Phase KW - Humans KW - Ligases KW - Maturation-Promoting Factor KW - metabolism KW - Mitosis KW - Neoplasm Proteins KW - Phosphorylation KW - Phosphotyrosine KW - Poly-ADP-Ribose Binding Proteins KW - Protein Kinases KW - Protein Processing, Post-Translational KW - Protein Serine-Threonine Kinases KW - Protein Structure, Tertiary KW - Proto-Oncogene Proteins KW - Ubiquitin KW - Ubiquitin-Protein Ligases KW - Xenopus KW - Xenopus Proteins KW - Polo-Like Kinase 1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1083/jcb.200108016 ER -