TY  - GEN
AU  - Kent,Ute M
AU  - Mills,Danielle E
AU  - Rajnarayanan,Rajendram V
AU  - Alworth,William L
AU  - Hollenberg,Paul F
TI  - Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites
SN  - 0022-3565
PY  - 2002///0225
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Biotransformation
KW  - Chromatography, High Pressure Liquid
KW  - Cytochrome P-450 CYP2B1
KW  - antagonists & inhibitors
KW  - Cytochrome P-450 CYP2B6
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - biosynthesis
KW  - Enzyme Induction
KW  - drug effects
KW  - Ethinyl Estradiol
KW  - analogs & derivatives
KW  - Humans
KW  - In Vitro Techniques
KW  - Isoenzymes
KW  - Liver
KW  - Male
KW  - NADPH-Ferrihemoprotein Reductase
KW  - isolation & purification
KW  - Oxidoreductases, N-Demethylating
KW  - Phenobarbital
KW  - pharmacology
KW  - Rats
KW  - Rats, Long-Evans
KW  - Spectrophotometry, Ultraviolet
KW  - Steroid Hydroxylases
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1124/jpet.300.2.549
ER  -