Kent, Ute M <br/><br/>
Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Feb 2002 
 - 549-58 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Standard No.: </label>10.1124/jpet.300.2.549  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aryl Hydrocarbon Hydroxylases<br/>Biotransformation<br/>Chromatography, High Pressure Liquid<br/>Cytochrome P-450 CYP2B1--antagonists & inhibitors<br/>Cytochrome P-450 CYP2B6<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--biosynthesis<br/>Enzyme Induction--drug effects<br/>Ethinyl Estradiol--analogs & derivatives<br/>Humans<br/>In Vitro Techniques<br/>Isoenzymes--antagonists & inhibitors<br/>Liver--drug effects<br/>Male<br/>NADPH-Ferrihemoprotein Reductase--isolation & purification<br/>Oxidoreductases, N-Demethylating--antagonists & inhibitors<br/>Phenobarbital--pharmacology<br/>Rats<br/>Rats, Long-Evans<br/>Spectrophotometry, Ultraviolet<br/>Steroid Hydroxylases--antagonists & inhibitors<br/>Substrate Specificity