The impact of P-glycoprotein efflux on enterocyte residence time and enterocyte-based metabolism of verapamil. [electronic resource]
- The Journal of pharmacy and pharmacology Dec 2001
- 1611-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3573
10.1211/0022357011778214 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism Animals Aryl Hydrocarbon Hydroxylases Calcium Channel Blockers--metabolism Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System--physiology Dose-Response Relationship, Drug Enterocytes--metabolism Male Oxidoreductases, N-Demethylating--physiology Rats Rats, Sprague-Dawley Time Factors Verapamil--metabolism