TY - GEN AU - Krupa,Joanne C AU - Hasnain,Sadiq AU - Nägler,Dorit K AU - Ménard,Robert AU - Mort,John S TI - S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B SN - 0264-6021 PY - 2002///0312 KW - Amidohydrolases KW - metabolism KW - Aspartic Acid KW - chemistry KW - Binding Sites KW - Cathepsin B KW - Exopeptidases KW - Glutamic Acid KW - Histidine KW - Humans KW - Ions KW - Kinetics KW - Lysosomes KW - enzymology KW - Models, Molecular KW - Mutagenesis, Site-Directed KW - Mutation KW - Protein Binding KW - Protein Structure, Tertiary KW - Recombinant Proteins KW - Substrate Specificity KW - Tolbutamide KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1042/0264-6021:3610613 ER -