TY - GEN AU - Ruggeri,Bruce A AU - Robinson,Candy AU - Angeles,Thelma AU - Wilkinson,John AU - Clapper,Margie L TI - The chemopreventive agent oltipraz possesses potent antiangiogenic activity in vitro, ex vivo, and in vivo and inhibits tumor xenograft growth SN - 1078-0432 PY - 2002///0411 KW - Angiogenesis Inhibitors KW - therapeutic use KW - Animals KW - Anticarcinogenic Agents KW - Cell Division KW - drug effects KW - Dose-Response Relationship, Drug KW - Endothelium, Vascular KW - Hemangiosarcoma KW - blood supply KW - Humans KW - Insulin-Like Growth Factor I KW - metabolism KW - Liver KW - Male KW - Mice KW - Mice, Nude KW - Neovascularization, Pathologic KW - drug therapy KW - Oligonucleotide Array Sequence Analysis KW - methods KW - Pyrazines KW - Rats KW - Receptor Protein-Tyrosine Kinases KW - Receptor, Fibroblast Growth Factor, Type 4 KW - Receptors, Fibroblast Growth Factor KW - Receptors, Growth Factor KW - Receptors, Vascular Endothelial Growth Factor KW - Ribonuclease, Pancreatic KW - Thiones KW - Thiophenes KW - Transplantation, Heterologous KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -